Here is what we did with my ISA 428 preamp heat issue after installing an AD card. We added a heatsink (from an old 21" CRT, remember those...!!) with fan and some good heat transfer compound, a second smaller fan on the side wall (inside), a small rectifier/regulator circuit (***isolated from chassis ground) to power the fans and lastly, standoffs under the top cover to lift it up about a 1/2" and let more air in/out. Worked out great and all done from leftover recycled stuff laying around the shop.
Many thanks to Glenn L for the tech wizardry and Clovis L for the milling magic.